Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 13/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007314 | 0.93 | LMNA (0.40) | ALOX5APALOX5STAT3PTGS1PTGS2 | |
| SCHEMBL2004879 | 0.92 | ALOX5AP (0.33) | ALOX5APALOX5STAT3 | |
| SCHEMBL2004742 | 0.91 | STAT3 (0.35) | ALOX5APALOX5STAT3 | |
| SCHEMBL2007194 | 0.90 | ALOX5AP (0.42) | ALOX5APALOX5STAT3PTGS1PTGS2 | |
| SCHEMBL2011061 | 0.90 | ALOX5AP (0.39) | ALOX5APALOX5PTGS1PTGS2P2RX3 | |
| SCHEMBL1999358 | 0.90 | FAAH (0.41) | ALOX5APALOX5STAT3 | |
| SCHEMBL2007961 | 0.89 | STAT3 (0.34) | ALOX5APALOX5STAT3 | |
| SCHEMBL2005424 | 0.87 | ALOX5AP (0.42) | ALOX5APALOX5 | |
| SCHEMBL2001764 | 0.87 | ALOX5AP (0.39) | ALOX5APALOX5PTGS1PTGS2CNR2 | |
| SCHEMBL2008218 | 0.87 | ALOX5AP (0.41) | ALOX5APALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |