SCHEMBL2005133

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7713193	0.87	GABRB3 (0.62)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL3700705	0.84	TP53 (0.53)	TP53GAAMAPTNPC1RAB9A
	SCHEMBL14357210	0.82	ADORA1 (0.53)	TP53GAAMAPTNPC1RAB9A
	SCHEMBL1998899	0.81	SCN9A (0.41)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL2836888	0.81	GABRB3 (0.53)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL6586118	0.79	MAPT (0.57)	GAAMAPTSMN1; SMN2THRBKMT2A
	SCHEMBL12099796	0.76	NPSR1 (0.56)	TP53GAAMAPTNPC1RAB9A
	SCHEMBL14357211	0.75	SLC5A1 (0.50)	TP53GAAMAPTTHRBKMT2A
	SCHEMBL4701523	0.75	CHRNA7 (0.62)	GABRA2GABRB2TP53GAAMAPT
	SCHEMBL2835031	0.73	GABRB3 (0.49)	GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.