Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12785388 | 0.82 | MTNR1A (0.38) | MTNR1AMTNR1BALDH1A1ACACBKDM4E | |
| Hydrochloric Acid SCHEMBL6045018 | 0.80 | MTNR1A (0.37) | MTNR1AMTNR1BALDH1A1ACACBKDM4E | |
| SCHEMBL1668685 | 0.78 | ALDH1A1 (0.50) | MTNR1AMTNR1BALDH1A1ACACBKDM4E | |
| SCHEMBL795359 | 0.76 | ALDH1A1 (0.45) | MTNR1AMTNR1BALDH1A1ACACBKDM4E | |
| SCHEMBL4378947 | 0.76 | ALDH1A1 (0.45) | MTNR1AMTNR1BALDH1A1ACACBKDM4E | |
| SCHEMBL2766000 | 0.76 | ALDH1A1 (0.45) | MTNR1AMTNR1BALDH1A1ACACBKDM4E | |
| SCHEMBL6343473 | 0.75 | MEN1 (0.46) | MEN1FAAHMAPK1KMT2ATSHR | |
| SCHEMBL25633074 | 0.74 | MEN1 (0.42) | MEN1FAAHMAPK1KMT2ATSHR | |
| SCHEMBL25633073 | 0.74 | MEN1 (0.42) | MEN1FAAHMAPK1KMT2ATSHR | |
| SCHEMBL20245188 | 0.74 | MTNR1A (0.39) | MTNR1AMTNR1BALDH1A1ACACBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3522933-B1 | METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES | HOFFMANN LA ROCHE (CH) | 2021-12-15 | — | — | EP | disclosed |
| WO-2018065501-A1 | METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-04-12 | — | — | WO | disclosed |