Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865318 | 0.82 | KMT2A (0.42) | MEN1KMT2ALMNAHPGDGAA | |
| SCHEMBL6907438 | 0.82 | CYP1A1 (0.53) | MEN1KMT2AHPGDGAAPOLB | |
| SCHEMBL23071786 | 0.81 | SMN1; SMN2 (0.39) | MEN1KMT2ALMNAHPGDGAA | |
| SCHEMBL24279669 | 0.81 | LMNA (0.43) | MEN1KMT2ALMNAHPGDGAA | |
| SCHEMBL5640251 | 0.81 | GAA (0.56) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL6018151 | 0.80 | EPHX2 (0.53) | MEN1KMT2ALMNAGAAHDAC1 | |
| SCHEMBL23766042 | 0.79 | CA1 (0.58) | MEN1KMT2ALMNAHPGDGAA | |
| SCHEMBL19703283 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2ALMNAHPGDGAA | |
| SCHEMBL22987301 | 0.78 | LMNA (0.41) | MEN1KMT2ALMNAHPGDGAA | |
| SCHEMBL23783471 | 0.77 | KMT2A (0.48) | MEN1KMT2ALMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023234426-A1 | ANTIBODY-MULTIDRUG CONJUGATE | ＵＢＥ株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2022120132-A1 | ANTIBODY-OLIGONUCLEOTIDE COMPLEXES AND USES THEREOF | DYNE THERAPEUTICS, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2018065501-A1 | METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-04-12 | — | — | WO | disclosed |