Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.47 |
| ▸ | PGR | P06401 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004630 | 0.81 | NR3C1 (0.44) | NR3C1PGRCNR2SCN9ARORC | |
| SCHEMBL2006625 | 0.76 | ALPL (0.48) | NR3C1PGRCNR2CASR | |
| SCHEMBL2002847 | 0.76 | NR3C1 (0.45) | NR3C1PGRCNR2SCN9ARORC | |
| SCHEMBL2010022 | 0.70 | NR3C1 (0.54) | NR3C1PGRCNR2RORCCASR | |
| SCHEMBL2010021 | 0.70 | NR3C1 (0.54) | NR3C1PGRCNR2RORCCASR | |
| SCHEMBL2006930 | 0.68 | NR3C1 (0.78) | NR3C1PGRCASR | |
| SCHEMBL12570859 | 0.67 | FFAR4 (0.47) | SCN9ARORCCASRALOX5APFEN1 | |
| SCHEMBL2004237 | 0.65 | ALOX5AP (0.45) | SCN9ARORCCASRALOX5APFEN1 | |
| SCHEMBL2002144 | 0.65 | ALOX5AP (0.45) | SCN9ARORCCASRALOX5APFEN1 | |
| SCHEMBL2007353 | 0.64 | NR3C1 (0.85) | NR3C1PGRSCN9AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |