Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.78 |
| ▸ | PGR | P06401 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008107 | 0.88 | NR3C1 (1.00) | NR3C1PGRCASR | |
| SCHEMBL2004253 | 0.83 | NR3C1 (0.69) | NR3C1PGRCASR | |
| SCHEMBL2010050 | 0.79 | NR3C1 (0.67) | NR3C1PGRSMN1; SMN2CASR | |
| SCHEMBL2002007 | 0.78 | NR3C1 (0.82) | NR3C1PGRCASR | |
| SCHEMBL2002566 | 0.77 | NR3C1 (0.59) | NR3C1PGRSMN1; SMN2CASR | |
| SCHEMBL2007374 | 0.77 | NR3C1 (0.79) | NR3C1PGRS1PR1CASR | |
| SCHEMBL2005610 | 0.76 | NR3C1 (0.62) | NR3C1PGRMEN1ALDH1A1KMT2A | |
| SCHEMBL2005613 | 0.76 | NR3C1 (0.62) | NR3C1PGRMEN1ALDH1A1KMT2A | |
| SCHEMBL2008089 | 0.73 | NR3C1 (0.79) | NR3C1PGRS1PR1 | |
| SCHEMBL2008128 | 0.71 | NR3C1 (0.54) | NR3C1PGRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |