Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | CASP7 | P55210 | 4/20 | 0.43 |
| ▸ | CASP9 | P55211 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20356041 | 1.00 | CASP3 (0.43) | CASP3CASP1CASP7CASP9MEN1 | |
| SCHEMBL20052420 | 0.92 | CASP3 (0.47) | CASP3CASP1CASP7CASP9CTSL | |
| SCHEMBL20052423 | 0.92 | CASP3 (0.47) | CASP3CASP1CASP7CASP9CTSL | |
| SCHEMBL20356118 | 0.91 | CASP3 (0.42) | CASP3CASP1CASP7CASP9MEN1 | |
| SCHEMBL20052427 | 0.87 | CASP3 (0.61) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL7886933 | 0.84 | CTSK (0.53) | CASP3CASP1CASP7CASP9CTSL | |
| SCHEMBL20052454 | 0.83 | CASP3 (0.45) | CASP3CASP1CASP7CASP9CTSL | |
| SCHEMBL19944793 | 0.83 | CASP3 (0.45) | CASP3CASP1CASP7CASP9CTSL | |
| SCHEMBL20740990 | 0.83 | CASP3 (0.54) | CASP3CASP1CASP7CASP9CTSL | |
| SCHEMBL19015971 | 0.83 | CASP3 (0.54) | CASP3CASP1CASP7CASP9CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |