SCHEMBL20052633

SCHEMBL20052633

CC(C)(C)c1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccc(-c4ccc(-c5ccccc5)c(N(c5ccc(-c6ccccc6)cc5)C(C)(C)C)c4)cc3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
HSD17B2 P37059 1/20 0.35
DHODH Q02127 1/20 0.34
KIF11 P52732 2/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
CYP19A1 P11511 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
ASIC1 P78348 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
MEN1 O00255 1/20 0.32
NR2F2 P24468 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862783 0.89 MEN1 (0.36) ALOX5RXRARXRBNPC1RAB9A
SCHEMBL5787294 0.82 PTGES (0.38) PTGESALOX5HSD17B2DHODHKIF11
SCHEMBL21588501 0.80 PTGES (0.40) PTGESALOX5HSD17B2DHODHKIF11
SCHEMBL24206147 0.80 DHODH (0.47) PTGESALOX5HSD17B2DHODHKIF11
SCHEMBL22079658 0.80 PTGES (0.44) PTGESALOX5HSD17B2KIF11CYP19A1
SCHEMBL22079981 0.80 PTGES (0.44) PTGESALOX5HSD17B2KIF11CYP19A1
SCHEMBL18352212 0.80 KIF11 (0.46) PTGESALOX5HSD17B2DHODHKIF11
SCHEMBL24206102 0.80 KIF11 (0.46) PTGESALOX5HSD17B2DHODHKIF11
SCHEMBL23251119 0.80 GPR84 (0.36) PTGESALOX5DHODHKIF11RXRA
SCHEMBL16344297 0.80 KIF11 (0.48) PTGESALOX5HSD17B2DHODHKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9947878-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2018-04-17 US disclosed