Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21816474 | 0.80 | RPS6KA2 (0.40) | PTPN1PPARDALOX5PPARGHTR1A | |
| SCHEMBL12269849 | 0.78 | PTPN1 (0.39) | ALDH1A1PTPN1HPGDCYP3A4MAPK1 | |
| SCHEMBL20726997 | 0.78 | PTPN1 (0.39) | ALDH1A1PTPN1HPGDCYP3A4MAPK1 | |
| SCHEMBL16955777 | 0.77 | ABCB1 (0.53) | ALDH1A1HPGDCYP3A4MAPK1KDM4E | |
| SCHEMBL2446604 | 0.76 | PTPN1 (0.39) | ALDH1A1PTPN1PPARDHPGDKDM4E | |
| SCHEMBL17356791 | 0.73 | ABCB1 (0.42) | HPGDHTR1AABCB1 | |
| SCHEMBL21231927 | 0.72 | HTR1A (0.39) | ALDH1A1LMNAMAPTHTR1AADRA1A | |
| SCHEMBL935859 | 0.71 | HTR2C (0.50) | ADRA1ACA12CA1CA2CA4 | |
| SCHEMBL29474981 | 0.71 | HTR2C (0.50) | ADRA1ACA12CA1CA2CA4 | |
| SCHEMBL6484237 | 0.71 | HTR2C (0.50) | ADRA1ACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |