SCHEMBL17356791

SCHEMBL17356791

COc1cccc(C)c1C1CCCCC1C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.42
HTR1A P08908 7/20 0.39
HPGD P15428 1/20 0.39
TAS1R3 Q7RTX0 4/20 0.38
TAS1R1 Q7RTX1 4/20 0.38
TAS1R2 Q8TE23 3/20 0.38
HSD11B1 P28845 1/20 0.37
DRD2 P14416 1/20 0.36
HCRTR1 O43613 1/20 0.36
HCRTR2 O43614 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356793 0.86 ABCB1 (0.43) ABCB1HTR1ATAS1R3TAS1R1HSD11B1
SCHEMBL17356807 0.85 HTR1A (0.40) ABCB1HTR1AHPGDTAS1R3TAS1R1
SCHEMBL17356810 0.79 ADRA1A (0.42) ABCB1HTR1ADRD2
SCHEMBL17356785 0.78 HTR1A (0.38) ABCB1HTR1ADRD2HCRTR1HCRTR2
SCHEMBL17356787 0.78 HTR2C (0.40) HPGDHSD11B1
SCHEMBL16955777 0.75 ABCB1 (0.53) ABCB1HTR1AHPGDDRD2HCRTR1
SCHEMBL10123010 0.75 HTR2C (0.49) TAS1R3TAS1R1HSD11B1DRD2
SCHEMBL17356792 0.75 HTR2C (0.49) TAS1R3TAS1R1HSD11B1DRD2
SCHEMBL17356789 0.73 TAS1R3 (0.44) TAS1R3TAS1R1TAS1R2
SCHEMBL27881934 0.73 ALDH1A1 (0.43) TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313792-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN POLYMER THE UNIVERSITY OF TOKYO (JP) 2017-11-02 US disclosed
US-9499644-B2 Production method of polar group-containing olefin polymers SHOWA DENKO K.K. (JP) 2016-11-22 US disclosed
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS SHOWA DENKO K.K. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS OR10J3, OPRM1, ORC3 ABCB1 3562/4885HTR1A 3188/4885HPGD 1053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.