SCHEMBL20053098

SCHEMBL20053098

CC(=O)/C=C(\O)NC(C)CO

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
KCNK3 O14649 1/20 0.35
THRB P10828 1/20 0.35
CNR2 P34972 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CNR1 P21554 4/20 0.33
TGFBR1 P36897 1/20 0.33
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19621336 0.83 MMP1 (0.44) ALDH1A1
SCHEMBL19621312 0.80 POLB (0.44) ALDH1A1THRBTDP1MAPK1
SCHEMBL20053112 0.78 ALDH1A1 (0.43) ALDH1A1MAPK1
SCHEMBL20053113 0.76 LMNA (0.39) TDP1CNR1TGFBR1
SCHEMBL48911 0.72
SCHEMBL2633929 0.72
SCHEMBL48766 0.72
SCHEMBL1231366 0.72
SCHEMBL982687 0.72
SCHEMBL3306665 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed