Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24943437 | 0.85 | LMNA (0.43) | LMNAHSD17B10MMP8TSHRCYP3A4 | |
| SCHEMBL13227842 | 0.85 | MMP8 (0.33) | MMP8FAAH | |
| SCHEMBL14399745 | 0.82 | LMNA (0.41) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL14296154 | 0.78 | MMP8 (0.32) | MMP8TSHRFAAH | |
| SCHEMBL14296191 | 0.78 | MMP8 (0.32) | MMP8TSHRFAAH | |
| SCHEMBL14296192 | 0.78 | MMP8 (0.32) | MMP8TSHRFAAH | |
| SCHEMBL3258934 | 0.77 | LMNA (0.47) | LMNAFAAH | |
| SCHEMBL3764447 | 0.77 | TSHR (0.38) | TSHRCYP3A4 | |
| SCHEMBL13227576 | 0.77 | MMP8 (0.33) | MMP8FAAH | |
| SCHEMBL12044661 | 0.75 | LMNA (0.42) | LMNAHSD17B10MMP8TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943609-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |