Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10023659 | 0.83 | ALDH1A1 (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18030136 | 0.80 | ALDH1A1 (0.36) | TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL709254 | 0.77 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL23559881 | 0.77 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL713578 | 0.76 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL712371 | 0.76 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1321544 | 0.76 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1537080 | 0.76 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11792800 | 0.75 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1286178 | 0.75 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778768-A1 | FLUORINATED ACRYLATE BLOCK COPOLYMERS WITH LOW DYNAMIC SURFACE TENSION | BASF SE (DE) | 2021-02-17 | — | — | EP | disclosed |
| US-9944786-B2 | Method to lower the dynamic surface tension of a composition | BASF SE (DE) | 2018-04-17 | — | — | US | disclosed |