SCHEMBL15087770

SCHEMBL15087770

C[C@H](O)CNC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
CA9 Q16790 7/20 0.58
ALB P02768 1/20 0.55
MEN1 O00255 2/20 0.55
POLB P06746 2/20 0.55
KMT2A Q03164 2/20 0.55
ALPL P05186 1/20 0.55
ALPI P09923 1/20 0.55
ALPG P10696 1/20 0.55
ESR1 P03372 1/20 0.53
FOLH1 Q04609 2/20 0.53
SLC5A2 P31639 1/20 0.52
CA1 P00915 5/20 0.51
CA2 P00918 5/20 0.51
CA12 O43570 3/20 0.51
CA14 Q9ULX7 2/20 0.51
ATM Q13315 1/20 0.50
PLEC Q15149 1/20 0.50
HAVCR2 Q8TDQ0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153957 0.89 USP2 (0.66) USP2L3MBTL1CA9ALBMEN1
SCHEMBL23258882 0.87 USP2 (0.63) USP2L3MBTL1CA9ALBMEN1
SCHEMBL20053383 0.87 USP2 (0.66) USP2L3MBTL1CA9ALBMEN1
SCHEMBL92536 0.86 USP2 (0.62) USP2L3MBTL1CA9ALBMEN1
SCHEMBL16153102 0.86 USP2 (0.64) USP2L3MBTL1CA9ALBMEN1
SCHEMBL10138306 0.86 USP2 (0.69) USP2L3MBTL1CA9ALBMEN1
SCHEMBL13656547 0.86 USP2 (0.72) USP2L3MBTL1CA9ALBMEN1
SCHEMBL15143443 0.85 USP2 (0.63) USP2L3MBTL1CA9ALBMEN1
SCHEMBL9906230 0.85 USP2 (0.66) USP2L3MBTL1CA9ALBMEN1
SCHEMBL13287065 0.85 USP2 (0.60) USP2L3MBTL1CA9ALBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797946-B1 SIALIC ACID DIMERS BROSSMER REINHARD (DE) 2016-05-04 EP disclosed
US-9260467-B2 Sialic acid dimers BROSSMER REINHARD (DE) 2016-02-16 US disclosed
US-20150005245-A1 Sialic Acid Dimers BROSSMER REINHARD (DE) 2015-01-01 US disclosed
WO-2013097942-A1 SIALIC ACID DIMERS BROSSMER REINHARD (DE) 2013-07-04 WO disclosed
EP-2610263-A1 Sialic acid dimers Brossmer, Reinhard (DE) 2013-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150005245-A1 Sialic Acid Dimers SIGLEC9, SIGLEC7, NEU2 USP2 3507/4885L3MBTL1 4432/4885CA9 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.