Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | NMT2 | O60551 | 2/20 | 0.48 |
| ▸ | NMT1 | P30419 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 8/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20017023 | 0.89 | NMT1 (0.55) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL22692615 | 0.88 | NMT2 (0.47) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL24119975 | 0.87 | NMT2 (0.46) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL22692674 | 0.85 | NMT1 (0.52) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL24645937 | 0.85 | NMT2 (0.52) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL18879491 | 0.84 | GLP1R (0.49) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL21251694 | 0.84 | TLR2 (0.50) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL18973016 | 0.83 | NMT1 (0.48) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL20016499 | 0.83 | NMT1 (0.50) | TLR2NMT2NMT1GLP1RNOD1 | |
| SCHEMBL22692618 | 0.83 | NMT2 (0.53) | TLR2NMT2NMT1GLP1RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943604-B2 | Targeted therapeutic nucleosides and their use | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-17 | — | — | US | disclosed |