Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538886 | 0.91 | SCN9A (0.41) | GPR119HRH3HDAC4 | |
| SCHEMBL15540140 | 0.91 | SCN9A (0.41) | GPR119HRH3HDAC4 | |
| SCHEMBL15538890 | 0.91 | SCN9A (0.41) | GPR119HRH3HDAC4 | |
| SCHEMBL21534807 | 0.90 | GPR119 (0.43) | GPR119HPGDHRH3CYP2D6KCNH2 | |
| SCHEMBL15539576 | 0.89 | HDAC4 (0.43) | GPR119HRH3KCNH2LIPEHDAC4 | |
| SCHEMBL15539579 | 0.89 | HDAC4 (0.43) | GPR119HRH3KCNH2LIPEHDAC4 | |
| SCHEMBL21534684 | 0.88 | GPR119 (0.39) | GPR119LIPE | |
| SCHEMBL15539552 | 0.88 | HPGDS (0.42) | GPR119KCNH2LIPE | |
| SCHEMBL21534646 | 0.88 | GPR119 (0.59) | GPR119HPGDHRH3CYP2D6ADRB2 | |
| SCHEMBL20053536 | 0.87 | GPR119 (0.40) | GPR119HPGDHRH3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |