Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053739 | 0.94 | ADRB2 (0.45) | HRH3KDM1AKCNH2HPGDSSTR5 | |
| SCHEMBL15538608 | 0.91 | GRM3 (0.43) | HRH3KDM1AKCNH2SSTR5ALDH1A1 | |
| SCHEMBL15538606 | 0.91 | GRM3 (0.43) | HRH3KDM1AKCNH2SSTR5ALDH1A1 | |
| SCHEMBL20053605 | 0.90 | HRH3 (0.44) | HRH3KDM1AKCNH2HPGDSSTR5 | |
| SCHEMBL15538721 | 0.89 | HRH3 (0.55) | HRH3HPGDADRB2ALDH1A1KDM4E | |
| SCHEMBL15539248 | 0.88 | SSTR5 (0.51) | KCNH2SSTR5RBP4 | |
| SCHEMBL15537715 | 0.88 | HRH3 (0.56) | HRH3HPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20053594 | 0.87 | GPR119 (0.46) | HRH3ADRB2RBP4 | |
| SCHEMBL15539452 | 0.86 | SSTR5 (0.43) | KCNH2SSTR5 | |
| SCHEMBL20053601 | 0.86 | KDM1A (0.44) | HRH3KDM1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |