Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539951 | 0.90 | SSTR5 (0.47) | KDM1A | |
| SCHEMBL20053739 | 0.89 | ADRB2 (0.45) | HRH3GPR119KDM1AKMT2AMEN1 | |
| SCHEMBL20053644 | 0.89 | GPR119 (0.40) | HRH3GPR119KDM1A | |
| SCHEMBL15537713 | 0.88 | EGFR (0.41) | KDM1A | |
| SCHEMBL16803740 | 0.86 | SPHK2 (0.43) | HRH3L3MBTL1 | |
| SCHEMBL15537715 | 0.86 | HRH3 (0.56) | HRH3GPR119KMT2AMEN1HPGD | |
| SCHEMBL15538934 | 0.86 | SSTR5 (0.47) | — | |
| SCHEMBL15538721 | 0.86 | HRH3 (0.55) | HRH3KMT2AMEN1HPGDKDM4E | |
| SCHEMBL21534990 | 0.84 | XDH (0.46) | HRH3GPR119 | |
| SCHEMBL20053580 | 0.84 | HRH3 (0.44) | HRH3KDM1AHPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |