Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | CPS1 | P31327 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537547 | 0.92 | ALOX5AP (0.45) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL15537545 | 0.92 | ALOX5AP (0.45) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL15538644 | 0.92 | ALOX5AP (0.45) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL20053607 | 0.91 | GPR119 (0.44) | PARP10PARP15CPS1KCNH2HRH3 | |
| SCHEMBL16803846 | 0.91 | CPS1 (0.44) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL20053644 | 0.91 | GPR119 (0.40) | PARP10PARP15CPS1KCNH2HRH3 | |
| SCHEMBL15537974 | 0.90 | ALOX5AP (0.44) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL15539959 | 0.90 | ALOX5AP (0.44) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL15537977 | 0.90 | ALOX5AP (0.44) | PARP10PARP15CPS1GPR119SCN9A | |
| SCHEMBL20053739 | 0.90 | ADRB2 (0.45) | KCNH2HRH3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |