Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | CPS1 | P31327 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | WNT1 | P04628 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803881 | 0.89 | PARP1 (0.38) | CHRM4MTORPIK3CA | |
| SCHEMBL21535109 | 0.89 | CHRM4 (0.37) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL15537666 | 0.89 | CHRM4 (0.47) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534964 | 0.85 | HRH3 (0.43) | HRH3SSTR5 | |
| SCHEMBL16803776 | 0.85 | PREP (0.40) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL15539844 | 0.84 | SSTR5 (0.44) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL20053607 | 0.83 | GPR119 (0.44) | KCNH2HRH3CHRM2CHRM5CHRM1 | |
| SCHEMBL20053541 | 0.81 | SLC6A9 (0.41) | KCNH2HRH3CHRM4CHRM2CHRM5 | |
| SCHEMBL21535011 | 0.80 | HTR2A (0.48) | KCNH2HRH3CHRM4CHRM2CHRM5 | |
| SCHEMBL21534921 | 0.79 | DYRK1A (0.43) | KCNH2HRH3CHRM4NR3C1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |