Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CPS1 | P31327 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053623 | 0.92 | SLC6A9 (0.39) | SLC6A9KCNH2HRH3CPS1GPR119 | |
| SCHEMBL15538965 | 0.91 | PIK3CA (0.43) | SLC6A9GPR119SCN9ARBP4PIK3CA | |
| SCHEMBL20053539 | 0.91 | XDH (0.42) | SLC6A9KCNH2HRH3GPR119MTOR | |
| SCHEMBL15539342 | 0.91 | PIK3CA (0.43) | SLC6A9GPR119SCN9ARBP4PIK3CA | |
| SCHEMBL15538969 | 0.91 | PIK3CA (0.43) | SLC6A9GPR119SCN9ARBP4PIK3CA | |
| SCHEMBL16803845 | 0.91 | CPS1 (0.41) | SLC6A9KCNH2CPS1GPR119RBP4 | |
| SCHEMBL20053607 | 0.91 | GPR119 (0.44) | KCNH2HRH3CPS1GPR119CHRM2 | |
| SCHEMBL15538572 | 0.89 | PIK3CA (0.41) | SLC6A9CPS1GPR119SCN9ARBP4 | |
| SCHEMBL15538015 | 0.89 | PIK3CA (0.41) | SLC6A9CPS1GPR119SCN9ARBP4 | |
| SCHEMBL15538017 | 0.89 | PIK3CA (0.41) | SLC6A9CPS1GPR119SCN9ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |