Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448465 | 0.87 | KMT2A (0.67) | LTB4RKMT2AMEN1MAPK1GAA | |
| SCHEMBL2217173 | 0.87 | LTB4R (0.66) | LTB4RKMT2AMEN1MAPK1GAA | |
| SCHEMBL15754270 | 0.85 | LTB4R (0.64) | LTB4RKMT2AMEN1MAPK1GAA | |
| SCHEMBL30362093 | 0.85 | LTB4R (0.64) | LTB4RKMT2AMEN1MAPK1GAA | |
| SCHEMBL7531177 | 0.85 | LTB4R (0.68) | LTB4RKMT2AMEN1MAPK1GAA | |
| SCHEMBL9468747 | 0.82 | KMT2A (0.82) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL10684407 | 0.82 | SMN1; SMN2 (0.68) | KMT2AMEN1GAAALDH1A1POLB | |
| SCHEMBL3757797 | 0.82 | KMT2A (0.73) | KMT2AMEN1MAPK1GAAALDH1A1 | |
| SCHEMBL21665117 | 0.82 | LTB4R (0.63) | LTB4RKMT2AMEN1MAPK1GAA | |
| SCHEMBL16098600 | 0.82 | GSTO1 (0.48) | LTB4RKMT2AMAPK1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944612-B2 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-17 | — | — | US | disclosed |