Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | RXRB | P28702 | 2/20 | 0.56 |
| ▸ | RXRG | P48443 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082606 | 0.86 | GLA (0.50) | RXRARXRBRXRGSMN1; SMN2CA12 | |
| SCHEMBL8510655 | 0.84 | MGLL (0.49) | RXRARXRBRXRGSMN1; SMN2HDAC3 | |
| SCHEMBL514697 | 0.82 | MGLL (0.59) | RXRARXRBRXRGSMN1; SMN2HDAC3 | |
| SCHEMBL10067001 | 0.82 | GLA (0.47) | RXRARXRBRXRGSMN1; SMN2CA12 | |
| Hydrochloric Acid SCHEMBL28737900 | 0.81 | MGLL (0.58) | RXRARXRBRXRGSMN1; SMN2HDAC3 | |
| SCHEMBL15867924 | 0.80 | KMT2A (0.42) | RXRARXRBRXRGSMN1; SMN2CA12 | |
| SCHEMBL17449519 | 0.80 | KMT2A (0.42) | RXRARXRBRXRGSMN1; SMN2CA12 | |
| SCHEMBL22184094 | 0.80 | CA12 (0.59) | CA12CA1CA9KMT2AHPGD | |
| Hydrazine SCHEMBL27822007 | 0.79 | MGLL (0.56) | RXRARXRBRXRGSMN1; SMN2HDAC3 | |
| SCHEMBL20053829 | 0.79 | ALDH1A1 (0.59) | RXRARXRBRXRGSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950077-B2 | Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof | BIOALLIANCE C.V. (NL) | 2018-04-24 | — | — | US | disclosed |
| US-9943610-B2 | Hydrophilic self-immolative linkers and conjugates thereof | BIOALLIANCE C.V. (NL) | 2018-04-17 | — | — | US | disclosed |