Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727192 | 0.91 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TDP1USP2MAPT | |
| SCHEMBL5124270 | 0.82 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TDP1USP2MAPT | |
| SCHEMBL17507087 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2USP2MAPTLMNA | |
| SCHEMBL6597563 | 0.81 | USP2 (0.56) | ALDH1A1USP2MAPTLMNAHPGD | |
| SCHEMBL1907807 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2USP2MAPTLMNA | |
| SCHEMBL6788342 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2USP2MAPTLMNA | |
| SCHEMBL20053772 | 0.79 | RXRA (0.56) | ALDH1A1RXRARXRBRXRGSMN1; SMN2 | |
| SCHEMBL10553855 | 0.78 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TDP1MAPTLMNA | |
| SCHEMBL19144089 | 0.78 | USP2 (0.54) | ALDH1A1USP2MAPTLMNAS1PR1 | |
| SCHEMBL1675924 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2USP2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943610-B2 | Hydrophilic self-immolative linkers and conjugates thereof | BIOALLIANCE C.V. (NL) | 2018-04-17 | — | — | US | disclosed |