Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967314 | 0.83 | MLYCD (0.36) | MLYCDLMNAMEN1KMT2AMMP1 | |
| SCHEMBL15114441 | 0.81 | MLYCD (0.35) | MLYCDLMNAMEN1KMT2AMMP1 | |
| SCHEMBL15116621 | 0.81 | MLYCD (0.35) | MLYCDLMNAMEN1KMT2AMMP1 | |
| SCHEMBL4157715 | 0.79 | LMNA (0.42) | LMNAMEN1KMT2AMMP1MMP2 | |
| SCHEMBL15125146 | 0.79 | MLYCD (0.34) | MLYCDLMNAMEN1KMT2AMMP1 | |
| SCHEMBL19388202 | 0.79 | MLYCD (0.34) | MLYCDLMNAMEN1KMT2AMMP1 | |
| SCHEMBL15114442 | 0.76 | ALDH1A1 (0.35) | MLYCDLMNAMEN1KMT2A | |
| SCHEMBL15113688 | 0.76 | MLYCD (0.33) | MLYCDLMNA | |
| SCHEMBL967624 | 0.76 | MLYCD (0.37) | MLYCDLMNAMEN1KMT2AMMP1 | |
| SCHEMBL967623 | 0.76 | MLYCD (0.37) | MLYCDLMNAMEN1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |