Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12912376 | 0.84 | RAPGEF4 (0.39) | CES2PDE2AIDO1MEN1KMT2A | |
| SCHEMBL13326020 | 0.82 | PDE2A (0.33) | CES2PDE2AIDO1MEN1KMT2A | |
| SCHEMBL9465131 | 0.82 | PTPN5 (0.44) | CES2PDE2AIDO1MEN1KMT2A | |
| SCHEMBL1531168 | 0.82 | PDE2A (0.37) | CES2PDE2ATSHRALDH1A1CYP3A4 | |
| SCHEMBL543287 | 0.82 | PDE2A (0.33) | CES2PDE2AIDO1 | |
| SCHEMBL11039041 | 0.82 | PDE2A (0.33) | CES2PDE2AIDO1 | |
| SCHEMBL15850519 | 0.79 | CES2 (0.39) | CES2PDE2AIDO1TSHRALDH1A1 | |
| SCHEMBL29937091 | 0.78 | ALOX5AP (0.37) | CES2PDE2AIDO1 | |
| SCHEMBL20817217 | 0.78 | CES2 (0.35) | CES2IDO1 | |
| SCHEMBL27494719 | 0.78 | PDE2A (0.32) | CES2PDE2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371861-B2 | Process for preparing ring-fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2008-05-13 | — | — | US | claimed |
| EP-1616863-A1 | Process for the preparation of fluorinated aromatic compounds | LANXESS Deutschland GmbH (DE) | 2006-01-18 | — | — | EP | claimed |
| US-20060009643-A1 | Process for preparing ring-fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2006-01-12 | — | — | US | claimed |
| EP-0034402-B1 | METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | claimed |
| US-4384135-A | REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-17 | — | — | US | claimed |
| EP-0034402-A2 | Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | claimed |
| JP-62289534-A | — | — | None | — | — | JP | disclosed |
| JP-1246232-A | — | — | None | — | — | JP | disclosed |
| JP-5238985-A | — | — | None | — | — | JP | disclosed |
| WO-2026106260-A1 | NOVEL DIPHENYLETHER DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2026-05-21 | — | — | WO | disclosed |
| CN-119241408-A | Trifluoro methyl sulfide molecule as HIF2a inhibitor | 维眸生物科技(浙江)有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-11548854-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-01-10 | — | — | US | disclosed |
| US-11332448-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2022-05-17 | — | — | US | disclosed |
| EP-0180057-A1 | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-07 | — | — | EP | disclosed |
| EP-0034402-B1 | METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4388472-A | Substituted diphenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-14 | — | — | US | disclosed |
| US-4384135-A | REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-17 | — | — | US | disclosed |
| EP-0023100-B1 | HERBICIDAL COMPOSITIONS COMPRISING A DIPHENYL ETHER COMPOUND IN ADMIXTURE WITH ANOTHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-10 | — | — | EP | disclosed |
| EP-0034402-A2 | Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| EP-0023100-A1 | Herbicidal compositions comprising a diphenyl ether compound in admixture with another herbicide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009643-A1 | Process for preparing ring-fluorinated aromatics | FLI1, CYP4X1, AFF1 | CES2 1285/4885PDE2A 4829/4885IDO1 2060/4885 |
| US-11548854-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | CES2 753/4885PDE2A 712/4885IDO1 1350/4885 |
| US-11332448-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | CES2 753/4885PDE2A 712/4885IDO1 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.