Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397097 | 0.84 | ALDH1A1 (0.33) | DGAT1OPRL1KDM4EKMT2A | |
| SCHEMBL15116908 | 0.81 | FABP4 (0.30) | — | |
| SCHEMBL15125205 | 0.79 | — | — | |
| SCHEMBL15116722 | 0.79 | — | — | |
| SCHEMBL19388477 | 0.76 | — | — | |
| SCHEMBL17827419 | 0.75 | CTSS (0.30) | CTSK | |
| SCHEMBL476236 | 0.72 | KDM4E (0.53) | DGAT1OPRL1KDM4EKMT2ACTSK | |
| SCHEMBL13804337 | 0.71 | — | — | |
| SCHEMBL12397058 | 0.69 | OPRL1 (0.34) | OPRL1KDM4EKMT2A | |
| SCHEMBL20221468 | 0.68 | HTT (0.37) | DGAT1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |