Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116552 | 0.79 | MAPK1 (0.30) | — | |
| SCHEMBL5172495 | 0.77 | FFAR3 (0.38) | LMNABLMPMP22SMN1; SMN2 | |
| SCHEMBL15125209 | 0.75 | — | — | |
| SCHEMBL1872142 | 0.73 | PKM (0.31) | PKML3MBTL1 | |
| SCHEMBL15114280 | 0.71 | — | — | |
| SCHEMBL15931353 | 0.71 | NPSR1 (0.38) | ALDH1A1 | |
| SCHEMBL11928221 | 0.71 | — | — | |
| SCHEMBL26111678 | 0.71 | — | — | |
| SCHEMBL20054406 | 0.71 | PKM (0.33) | PKMLMNAALOX15BLMPMP22 | |
| SCHEMBL20054289 | 0.71 | L3MBTL1 (0.36) | PKMLMNAALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |