SCHEMBL1872142

SCHEMBL1872142

CC1(C)CCOC(C)(C(N)=O)O1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28179737 0.81 FFAR3 (0.37) L3MBTL1
SCHEMBL18064173 0.78 PKM (0.33) PKML3MBTL1
SCHEMBL20054427 0.73 PKM (0.36) PKML3MBTL1
SCHEMBL19311494 0.70
SCHEMBL22124955 0.67 PKM (0.31) PKML3MBTL1
SCHEMBL20054289 0.65 L3MBTL1 (0.36) PKML3MBTL1
SCHEMBL6816522 0.64
SCHEMBL12997215 0.64
SCHEMBL20221108 0.64 L3MBTL1 (0.33) L3MBTL1
SCHEMBL2223361 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2498608-A1 BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS GlaxoSmithKline LLC (US) 2012-09-19 EP disclosed
WO-2011059610-A1 BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS GLAXOSMITHKLINE LLC (US) 2011-05-19 WO disclosed