Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054529 | 0.86 | AAK1 (0.46) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL20054554 | 0.86 | AAK1 (0.46) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL20054511 | 0.84 | CACNA1H (0.49) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL20054430 | 0.81 | AAK1 (0.41) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL19488605 | 0.79 | PDE10A (0.35) | SCN10AKMT2APOLBAAK1KDM4E | |
| SCHEMBL20054454 | 0.74 | SCN10A (0.36) | SCN10APDE10A | |
| SCHEMBL19488589 | 0.73 | AAK1 (0.36) | SCN10AAAK1MAPTKDM4EPDE10A | |
| SCHEMBL20054433 | 0.72 | AAK1 (0.52) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL15116602 | 0.71 | SCN10A (0.40) | SCN10AAAK1 | |
| SCHEMBL19388443 | 0.71 | SCN10A (0.40) | SCN10AAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |