Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054434 | 0.84 | SCN10A (0.38) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| Hydrochloric Acid SCHEMBL28836137 | 0.79 | KMT2A (0.75) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL20054433 | 0.79 | AAK1 (0.52) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL29409142 | 0.77 | TDP1 (0.70) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL19377986 | 0.77 | HDAC3 (0.52) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL4354084 | 0.77 | TDP1 (0.70) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| SCHEMBL38661663 | 0.77 | IDO1 (0.76) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| Hydrochloric Acid SCHEMBL23705615 | 0.76 | HDAC3 (0.51) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| Hydrochloric Acid SCHEMBL5204720 | 0.76 | TDP1 (0.68) | CACNA1HRAD52UBE2NIDO1KMT2A | |
| Hydrochloric Acid SCHEMBL31164757 | 0.76 | TDP1 (0.68) | CACNA1HRAD52UBE2NIDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |