Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400284 | 0.78 | SMN1; SMN2 (0.65) | ALDH1A1HPGDRAB9ASMN1; SMN2HTT | |
| SCHEMBL13489789 | 0.78 | KMT2A (0.49) | ALDH1A1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL20221643 | 0.78 | RORC (0.52) | ALDH1A1HPGDRAB9ASMN1; SMN2HTT | |
| SCHEMBL403018 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HPGDRAB9ASMN1; SMN2HTT | |
| SCHEMBL404902 | 0.75 | PPARG (0.41) | ALDH1A1HPGD | |
| SCHEMBL28939771 | 0.73 | RAB9A (0.66) | ALDH1A1HPGDRAB9ASMN1; SMN2HTT | |
| SCHEMBL10915926 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2AMEN1CYP2C19 | |
| Hydrochloric Acid SCHEMBL10946080 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AMEN1CYP2C19 | |
| SCHEMBL23222125 | 0.70 | MAPT (0.83) | ALDH1A1RAB9ASMN1; SMN2HTTKMT2A | |
| SCHEMBL19002441 | 0.69 | KMT2A (0.64) | ALDH1A1RAB9ASMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |