Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899942 | 0.78 | ALOX15 (0.32) | ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL20054783 | 0.76 | ALDH1A1 (0.37) | ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL27351221 | 0.74 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL1437686 | 0.74 | — | — | |
| SCHEMBL27813655 | 0.74 | — | — | |
| SCHEMBL24337131 | 0.72 | TSHR (0.39) | EPHX2ALOX15 | |
| SCHEMBL23883322 | 0.72 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL307206 | 0.71 | — | — | |
| SCHEMBL4359650 | 0.71 | CES2 (0.43) | ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL19592405 | 0.70 | ALOX15 (0.35) | EPHX2ALOX15CYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |