Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287260 | 0.85 | GAA (0.50) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL24938161 | 0.82 | RAB9A (0.47) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL11294798 | 0.82 | KDM4E (0.51) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL19345853 | 0.79 | TSHR (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTMAOA | |
| SCHEMBL8562167 | 0.79 | GAA (0.45) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL11293577 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL19699329 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL5674801 | 0.73 | EHMT2 (0.52) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL3888498 | 0.72 | MEN1 (0.55) | SMN1; SMN2GAAALDH1A1MAPTMAOA | |
| SCHEMBL29590223 | 0.72 | MEN1 (0.55) | SMN1; SMN2GAAALDH1A1MAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2019183523-A1 | HETERO-BIFUNCTIONAL DEGRADER COMPOUNDS AND THEIR USE AS MODULATORS OF TARGETED UBIQUINATION (VHL) | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| EP-3437641-A1 | INFLAMMATORY INTESTINAL DISEASE THERAPEUTIC AGENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-02-06 | — | — | EP | disclosed |
| EP-2863921-B1 | POLYMER-NSAID CONJUGATE | POLYACTIVA PTY LTD (AU) | 2018-04-18 | — | — | EP | disclosed |