Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 8/20 | 0.53 |
| ▸ | FABP3 | P05413 | 4/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.52 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401710 | 0.83 | NR4A3 (0.44) | FABP4FABP3FABP5FABP1MEN1 | |
| SCHEMBL23398985 | 0.83 | MEN1 (0.48) | FABP4FABP3FABP5FABP1MEN1 | |
| SCHEMBL8766292 | 0.83 | NPC1 (0.45) | FABP4FABP3MEN1KMT2ANPC1 | |
| SCHEMBL13013589 | 0.80 | POLB (0.58) | FABP4FABP3FABP5FABP1MEN1 | |
| SCHEMBL14365554 | 0.80 | FABP4 (0.56) | FABP4FABP3FABP5FABP1MEN1 | |
| Isofezolac SCHEMBL25481 | 0.79 | ALDH1A1 (0.52) | FABP4FABP3FABP5FABP1MEN1 | |
| SCHEMBL11405385 | 0.77 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3478412 | 0.76 | MEN1 (0.48) | FABP4FABP3FABP5FABP1MEN1 | |
| SCHEMBL23402133 | 0.75 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23401336 | 0.75 | NPC1 (0.42) | FABP4FABP3FABP5FABP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2863921-B1 | POLYMER-NSAID CONJUGATE | POLYACTIVA PTY LTD (AU) | 2018-04-18 | — | — | EP | disclosed |