Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 8/20 | 0.63 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.63 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.55 |
| ▸ | TUBB | P07437 | 8/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141265 | 0.84 | ALDH1A1 (0.60) | S1PR4S1PR1S1PR5ALDH1A1ALOX15 | |
| SCHEMBL20055168 | 0.83 | MPL (0.47) | S1PR4S1PR1S1PR5TUBB4ATUBB | |
| SCHEMBL18462602 | 0.82 | S1PR4 (0.67) | S1PR4S1PR1S1PR5TUBB4ATUBB | |
| SCHEMBL13034836 | 0.80 | ALDH1A1 (0.59) | S1PR4S1PR1S1PR5ALDH1A1ALOX15 | |
| SCHEMBL8192405 | 0.80 | ALDH1A1 (0.59) | S1PR4S1PR1S1PR5ALDH1A1ALOX15 | |
| SCHEMBL4240625 | 0.80 | ALDH1A1 (0.63) | S1PR4S1PR1S1PR5ALDH1A1ALOX15 | |
| SCHEMBL8083831 | 0.79 | TUBB4A (0.55) | S1PR4S1PR1S1PR5TUBB4ATUBB | |
| SCHEMBL3500728 | 0.79 | S1PR4 (0.59) | S1PR4S1PR1S1PR5TUBB4ATUBB | |
| SCHEMBL14450648 | 0.78 | S1PR4 (1.00) | S1PR4S1PR1S1PR5TUBB4ATUBB | |
| SCHEMBL9295731 | 0.78 | MPL (0.67) | S1PR4S1PR1S1PR5TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |