Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20055446 | 0.71 | ALDH1A1 (0.44) | MAPTL3MBTL1ALDH1A1RAB9APOLB | |
| SCHEMBL21768810 | 0.65 | ALDH1A1 (0.62) | MAPTL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25693259 | 0.63 | NPC1 (0.54) | ALDH1A1P2RX7RAB9APOLBSMN1; SMN2 | |
| SCHEMBL137308 | 0.62 | LMNA (0.65) | MAPTL3MBTL1ALDH1A1RAB9APOLB | |
| SCHEMBL12179110 | 0.62 | KMT2A (0.70) | MAPTL3MBTL1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL21442370 | 0.62 | MMP2 (0.58) | MAPTL3MBTL1ALDH1A1RAB9APOLB | |
| SCHEMBL13469241 | 0.61 | KMT2A (0.76) | MAPTL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL19863279 | 0.61 | ALDH1A1 (0.56) | MAPTL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7768532 | 0.61 | ALDH1A1 (0.56) | MAPTL3MBTL1ALDH1A1P2RX7RAB9A | |
| SCHEMBL24576746 | 0.61 | TDP1 (0.54) | MAPTL3MBTL1ALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |