Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20055688 | 0.87 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3786809 | 0.73 | PKM (0.46) | KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL3786803 | 0.73 | PKM (0.46) | KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL20055589 | 0.72 | PSEN1 (0.44) | KMT2AGNRHRMEN1ATM | |
| SCHEMBL20055697 | 0.72 | LMNA (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3783799 | 0.70 | EPHX1 (0.52) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3783804 | 0.70 | EPHX1 (0.52) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12615476 | 0.68 | TDP1 (0.44) | KMT2AGNRHRMEN1SMN1; SMN2 | |
| SCHEMBL1724542 | 0.68 | TDP1 (0.44) | KMT2AGNRHRMEN1SMN1; SMN2 | |
| SCHEMBL13356590 | 0.68 | FUCA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116526-B1 | DERIVATES OF SUBSTITUTED TARTARIC AICD AND USAGE FOR PREPARATING BETA SECRETASE INHIBITORS | INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2018-04-18 | — | — | EP | disclosed |