Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20055591 | 0.72 | KMT2A (0.37) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3780968 | 0.71 | ALDH1A1 (0.56) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3780965 | 0.71 | ALDH1A1 (0.56) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3780243 | 0.70 | LMNA (0.52) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3780235 | 0.70 | LMNA (0.52) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL20055626 | 0.70 | KMT2A (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3787349 | 0.68 | ALDH1A1 (0.49) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3789599 | 0.66 | KMT2A (0.50) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3785243 | 0.66 | KMT2A (0.50) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL14271233 | 0.65 | HSD17B10 (0.71) | LMNAHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116526-B1 | DERIVATES OF SUBSTITUTED TARTARIC AICD AND USAGE FOR PREPARATING BETA SECRETASE INHIBITORS | INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2018-04-18 | — | — | EP | disclosed |