Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056512 | 0.89 | HPGD (0.62) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL178430 | 0.75 | TAS1R3 (0.66) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL15341542 | 0.74 | NPC1 (0.54) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL242628 | 0.73 | MAPK11 (0.63) | MAPK14 | |
| SCHEMBL104335 | 0.73 | NPC1 (0.50) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL455691 | 0.73 | RAB9A (0.53) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL10282412 | 0.73 | RAB9A (0.86) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL3233932 | 0.73 | NPC1 (0.53) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL22490276 | 0.72 | HPGD (0.66) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL28378463 | 0.71 | HPGD (0.69) | HPGDNPC1RAB9ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |