Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CTSC | P53634 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20864018 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL24968500 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL24968735 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL22604163 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL16333024 | 0.80 | ALDH1A1 (0.41) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL14902251 | 0.80 | ALDH1A1 (0.41) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL1378574 | 0.79 | — | — | |
| SCHEMBL7211173 | 0.79 | CTSC (0.41) | CTSCACACBLMNA | |
| SCHEMBL20729541 | 0.78 | KMT2A (0.42) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL8402243 | 0.77 | CYP2C9 (0.50) | SMN1; SMN2GAAHPGDNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11566039-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-31 | — | — | US | disclosed |
| US-20220073554-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-03-10 | — | — | US | disclosed |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210087215-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-03-25 | — | — | US | disclosed |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-29 | — | — | US | disclosed |
| WO-2019032956-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | SMN1; SMN2 1440/4885GAA 615/4885HPGD 3563/4885 |
| US-11566039-B2 | Lincosamide antibiotics and uses thereof | NPEPPS, ASNS, LNPEP | SMN1; SMN2 1868/4885GAA 356/4885HPGD 2606/4885 |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | SMN1; SMN2 1440/4885GAA 615/4885HPGD 3563/4885 |
| US-20210087215-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | NPEPPS, ASNS, LNPEP | SMN1; SMN2 1868/4885GAA 356/4885HPGD 2606/4885 |
| US-20220073554-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | LNPEP, LCLAT1, NPEPPS | SMN1; SMN2 1317/4885GAA 796/4885HPGD 3117/4885 |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | LNPEP, LCLAT1, NPEPPS | SMN1; SMN2 1440/4885GAA 615/4885HPGD 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.