Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 9/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734929 | 0.83 | ERN1 (0.66) | ERN1HSD17B2HSD17B1PDK2 | |
| SCHEMBL29904856 | 0.82 | HSD17B1 (0.69) | ERN1HSD17B2HSD17B1ESR2HSD17B14 | |
| SCHEMBL20056514 | 0.82 | HSD17B1 (0.69) | HSD17B2HSD17B1ESR2HSD17B14 | |
| SCHEMBL28903928 | 0.82 | HSD17B1 (0.69) | ERN1HSD17B2HSD17B1ESR2HSD17B14 | |
| SCHEMBL18311613 | 0.82 | ERN1 (0.64) | ERN1HSD17B2HSD17B1PDK2LMNA | |
| SCHEMBL17795214 | 0.82 | ERN1 (0.60) | ERN1HSD17B2HSD17B1PDK2LMNA | |
| SCHEMBL10242017 | 0.81 | ERN1 (0.50) | ERN1HSD17B2HSD17B1ESR2PDK2 | |
| SCHEMBL20056592 | 0.81 | HSD17B1 (0.68) | ERN1HSD17B2HSD17B1ESR2HSD17B14 | |
| SCHEMBL20057639 | 0.81 | ERN1 (0.58) | ERN1HSD17B2PDK2LMNAHPGD | |
| SCHEMBL12767059 | 0.81 | ERN1 (1.00) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |