Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867054 | 0.81 | GAA (0.51) | LMNASMN1; SMN2L3MBTL1HPGDGAA | |
| SCHEMBL11773180 | 0.78 | RAB9A (0.50) | LMNASMN1; SMN2L3MBTL1HTTRAB9A | |
| SCHEMBL806076 | 0.77 | POLB (0.55) | LMNASMN1; SMN2L3MBTL1HPGDGAA | |
| SCHEMBL14613543 | 0.72 | GRIN2D (0.36) | LMNASMN1; SMN2PKMGAAHTT | |
| SCHEMBL4261423 | 0.71 | RXFP1 (0.38) | LMNASMN1; SMN2PKMHPGDGAA | |
| SCHEMBL12042083 | 0.70 | LMNA (0.41) | LMNASMN1; SMN2PKMHPGDHTT | |
| SCHEMBL24564675 | 0.70 | CYP1A2 (0.41) | LMNASMN1; SMN2L3MBTL1HPGDGAA | |
| SCHEMBL11772304 | 0.70 | RAB9A (0.49) | SMN1; SMN2HPGDGAAHTTRAB9A | |
| SCHEMBL787870 | 0.70 | PKM (0.62) | LMNASMN1; SMN2L3MBTL1PKMHPGD | |
| SCHEMBL22132855 | 0.69 | KMT2A (0.48) | LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709983-B1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-18 | — | — | EP | disclosed |