Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13034259 | 0.86 | POLB (0.54) | POLBLTA4H | |
| SCHEMBL2693506 | 0.85 | POLB (0.61) | POLBLTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6535590 | 0.85 | POLB (0.61) | POLBLTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6535532 | 0.85 | POLB (0.61) | POLBLTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8667461 | 0.82 | POLB (0.57) | POLBLTA4H | |
| SCHEMBL478125 | 0.80 | POLB (0.69) | POLBLTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11539185 | 0.78 | POLB (0.65) | POLBLTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20056668 | 0.76 | POLB (0.54) | POLBLTA4H | |
| SCHEMBL12133581 | 0.76 | POLB (0.54) | POLBLTA4H | |
| SCHEMBL9015256 | 0.76 | POLB (0.57) | POLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |