Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535532 | 0.95 | POLB (0.61) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2693506 | 0.95 | POLB (0.61) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6535590 | 0.95 | POLB (0.61) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11539185 | 0.90 | POLB (0.65) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10601127 | 0.87 | POLB (0.61) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8667461 | 0.84 | POLB (0.57) | POLBKMT2ALTA4H | |
| Acetamide SCHEMBL28036559 | 0.83 | POLB (0.49) | POLB | |
| SCHEMBL6981979 | 0.83 | HRH3 (0.48) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22652854 | 0.83 | HRH3 (0.55) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21357469 | 0.83 | HRH3 (0.48) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720721-B | Anion exchange polymer, ion exchange membrane, and preparation methods and application thereof | 国家电投集团氢能科技发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117720721-A | Anion exchange polymer, ion exchange membrane, and preparation methods and application thereof | 国家电投集团氢能科技发展有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117487047-A | Phosphonic acid functionalized polymer, multifunctional styrene polymer and application thereof | 国家电投集团氢能科技发展有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-11795315-B2 | Group 5 metal complexes for producing amine-functionalized polyolefins | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20220363786-A1 | GROUP 5 METAL COMPLEXES FOR PRODUCING AMINE-FUNTIONALIZED POLYOLEFINS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-11-17 | — | — | US | disclosed |
| US-11034707-B2 | Group 5 metal complexes for catalytic amine functionalization | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-06-15 | — | — | US | disclosed |
| US-20200352921-A1 | ARYL-SULFONAMIDE AND ARYL-SULFONE DERIVATIVES AS TRPML MODULATORS | CALYGENE BIOTECHNOLGY INC (US) | 2020-11-12 | — | — | US | disclosed |
| US-20200283459-A1 | GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-09-10 | — | — | US | disclosed |
| US-9567302-B2 | Carbamate compounds and of making and using same | ABIDE THERAPEUTICS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20150080364-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-RE30812-E | ANTIARRHTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| EP-0031885-A1 | Basic ethers, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4064254-A | ANTIARRHYTHMIC AND ANTISEROTONINE AGENTS | MEAD JOHNSON & COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |
| US-4000143-A | ANTIARRHYTHMIC AND ANTISEROTONIN AGENTS | MEAD JOHNSON & COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |
| US-3931195-A | ANTIARRHYTHMIA, ANTISEROTONIN | MEAD JOHNSON & COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352921-A1 | ARYL-SULFONAMIDE AND ARYL-SULFONE DERIVATIVES AS TRPML MODULATORS | TRPM6, TRPM2, TRPM5 | POLB 4634/4885CYP1A2 3131/4885CYP3A4 3143/4885 |
| US-20200283459-A1 | GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION | ADH5, PRMT5, MAOA | POLB 425/4885CYP1A2 114/4885CYP3A4 169/4885 |
| US-11034707-B2 | Group 5 metal complexes for catalytic amine functionalization | ADH5, PRMT5, MAOA | POLB 425/4885CYP1A2 114/4885CYP3A4 169/4885 |
| US-20150080364-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | CPS1, FABP4, VHL | POLB 3716/4885CYP1A2 2384/4885CYP3A4 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.