Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539185 | 0.95 | POLB (0.65) | POLBLTA4HKMT2A | |
| SCHEMBL6535590 | 0.89 | POLB (0.61) | POLBLTA4H | |
| SCHEMBL2693506 | 0.89 | POLB (0.61) | POLBLTA4H | |
| SCHEMBL6535532 | 0.89 | POLB (0.61) | POLBLTA4H | |
| SCHEMBL10601127 | 0.89 | POLB (0.61) | POLBLTA4HKMT2A | |
| SCHEMBL478125 | 0.84 | POLB (0.69) | POLBLTA4HKMT2A | |
| SCHEMBL20056786 | 0.82 | POLB (0.53) | POLBLTA4H | |
| SCHEMBL29139845 | 0.81 | SIGMAR1 (0.47) | — | |
| SCHEMBL9015256 | 0.79 | POLB (0.57) | POLBLTA4H | |
| SCHEMBL7404503 | 0.79 | SIGMAR1 (0.54) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876347-A1 | QUINOLINE DERIVATIVES | Smithkline Beecham S.p.A. (IT) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997021680-A1 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM S.P.A. (IT) | 1997-06-19 | — | — | WO | disclosed |