Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055430 | 0.78 | EPHX1 (0.58) | RAB9ASMN1; SMN2MCHR2MCHR1MEN1 | |
| SCHEMBL7106481 | 0.72 | KAT2B (0.56) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL13162978 | 0.72 | KAT2B (0.56) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL4443892 | 0.72 | KAT2B (0.56) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL8049469 | 0.71 | CTSL (0.67) | RAB9AMCHR2MCHR1CHRNB2CHRNA5 | |
| SCHEMBL16310962 | 0.68 | EPHX1 (0.51) | RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL22761843 | 0.68 | CHRNB2 (0.47) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL13220244 | 0.65 | CXCR4 (0.50) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL12506716 | 0.65 | FAP (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL29358366 | 0.65 | CHRNB2 (0.44) | RAB9ASMN1; SMN2CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |