Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23418149 | 0.83 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL22814733 | 0.81 | MEN1 (0.41) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL25789921 | 0.80 | TDP1 (0.41) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL439265 | 0.79 | ALDH1A1 (0.37) | TDP1 | |
| SCHEMBL2623719 | 0.78 | TDP1 (0.40) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL3043987 | 0.78 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL24668225 | 0.78 | TDP1 (0.38) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL14642773 | 0.76 | MEN1 (0.50) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL17771615 | 0.75 | MEN1 (0.37) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL12092148 | 0.75 | MEN1 (0.49) | MEN1GAAKMT2ATDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3308801-A1 | ANTIBODY DRUG CONJUGATE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USES THEREOF | XDCExplorer (Shanghai) Co., Ltd. (CN) | 2018-04-18 | — | — | EP | disclosed |