Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057096 | 0.78 | VSIR (0.45) | VSIRCD274 | |
| SCHEMBL20057341 | 0.78 | VSIR (0.45) | VSIRCD274 | |
| SCHEMBL20170535 | 0.72 | PKM (0.36) | NOTUM | |
| SCHEMBL20170522 | 0.72 | PKM (0.36) | NOTUM | |
| SCHEMBL19984999 | 0.71 | CD274 (0.56) | VSIRCD274PDCD1LG2 | |
| SCHEMBL19969059 | 0.70 | NOTUM (0.39) | MAPTL3MBTL1NOTUM | |
| SCHEMBL20057106 | 0.70 | VSIR (0.67) | VSIRCD274PDCD1LG2 | |
| SCHEMBL21738417 | 0.70 | VSIR (0.67) | VSIRCD274PDCD1LG2 | |
| SCHEMBL20057381 | 0.68 | VSIR (0.56) | VSIRCD274PDCD1LG2 | |
| SCHEMBL18078269 | 0.68 | VSIR (0.55) | VSIRCD274PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041828-B1 | 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-05-23 | — | — | EP | disclosed |