Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305505 | 0.70 | SMN1; SMN2 (0.33) | CYP1A2CYP3A4TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL16263024 | 0.67 | AR (0.33) | — | |
| SCHEMBL16241270 | 0.66 | MGLL (0.37) | ALDH1A1 | |
| SCHEMBL14627790 | 0.63 | — | — | |
| SCHEMBL18156637 | 0.63 | — | — | |
| SCHEMBL29745049 | 0.61 | ALDH1A1 (0.31) | HSD17B10ALDH1A1POLB | |
| SCHEMBL146714 | 0.60 | NPC1 (0.56) | CYP1A2CYP3A4ALDH1A1POLB | |
| SCHEMBL29745092 | 0.60 | ESR1 (0.31) | — | |
| SCHEMBL2882677 | 0.59 | DDB1 (0.60) | SMN1; SMN2 | |
| SCHEMBL16501134 | 0.59 | LMNA (0.38) | CYP1A2SMN1; SMN2HSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |